Nouvelles - Santé

L'OIM lance un projet pour améliorer la capacité de gestion des frontières

jeudi 1 janvier 1970

L'Organisation internationale pour les migrations (OIM) et les principaux acteurs de la migration du Ghana Health Service (GHS), le ministère de ...

[PARI GmbH, Omron, Drive DeVilbiss Healthcare] Connaissez-Vous Les Revenus Offerts Par Le ...

jeudi 1 janvier 1970

PARI GmbH, Omron, Drive DeVilbiss Healthcare sont quelques-unes des entreprises clés de l industrie Nébuliseur. En tant que bonne source de données ...

Sommeil : un accéléromètre pour repérer les maladies psychiatriques

jeudi 1 janvier 1970

*University of Toronto, Centre for Addiction and Mental Health (CAMH), Canada. **Les participants étaient âgés de 43 à 79 ans et 56% d'entre eux ...

Lutte contre le tabagisme : la proposition choc d’élus britanniques

jeudi 1 janvier 1970

That's why I've tabled amendments to the Health and Care Bill with the aim of reducing smoking levels and to make big tobacco pay for their ...

Mises À Jour Actuelles: Méthyltestostérone Marché Analyse De La Demande Par- Impax ...

jeudi 1 janvier 1970

Mises À Jour Actuelles: Méthyltestostérone Marché Analyse De La Demande Par- Impax Laboratories, Bausch Health, Harbin Pharmaceutical Group.

Source: mediCMS.be

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Articles médicaux

Androgen effects on neurosteroids and endogenous opioids - Abstract

oct. 14 2007

A.R. Genazzani, N. Pluchino - Department of Reproductive Medicine and Child Development
Division of Obstetrics and Gynecology, University of Pisa

Androgen arriving from the gonads via the circulation modulate brain function, affecting gender differentiation and sexually differentiated behavioral responses, but also the ability of the brain to process, store and retrieve sensory information. Gonadal steroids are being increasingly recognized as important factors influencing the endogenous opioid system and the neurosteroids milieu in both sexes, underlining the presence of additional hormone-related neurobiological mechanisms for gender differences of brain function. Beta-endorphin is the endogenous opiate that has received the most research attention: behavioral, analgesic, thermoregulatory and neuroendocrine properties of this peptide have been widely described and a role in the central drive of sexuality it has been recently evaluated. Furthermore, brain and plasma concentrations of neurosteroids have been found to modulate both behavioral and biochemical responses to acute and chronic stress, anxiety, depression, anaesthesia, sleep, memory and pain. These observations have suggested that the fluctuations of neurosteroids and modification of the beta-endorphin system could be involved in the development, course and prognosis of some mental disorders like depression, premenstrual dysphoria, anorexia and bulimia nervosa and Alzheimer’s disease. Though a large attention has been given to the study of estrogens role, relative attention and awareness has been focused on the activity of endogenous or exogenous androgens. Delta-5 and delta-4 androgens affect directly the endogenous beta-endorphin system and the neurosteroids milieu showing also a gender-related response. The present data, suggest additional clues in the neurobiology of gonadal steroids.